Analytical Method Development and Validation of Bendamustine in Bulk Using RP-HPLC

Analytical method development and validation of prasugrel in bulk and its pharmaceutical formulation using the RP-HPLC method

PURPOSE This study was designed to develop and validate a simple, sensitive, precise, and specific reverse phase high-performance liquid chromatographic (HPLC) method for the determination of prasugrel in bulk and its tablet dosage forms. MATERIALS AND METHODS The HPLC separation was carried out by reverse phase chromatography on an inertsil ODS-3V column (5 μm; 250 × 4.6mm(2)) with a mobile ...

RP-HPLC method development and validation for determination of eptifibatide acetate in bulk drug substance and pharmaceutical dosage forms

A new, rapid, economical and isocratic reverse phase high performance liquid chromatography (RP-HPLC) method was developed for the determination of eptifibatide acetate, a small synthetic antiplatelet peptide, in bulk drug substance and pharmaceutical dosage forms. The developed method was validated as per of ICH guidelines. The chromatographic separation was achieved isocratically on C18 colum...

RP-HPLC method development and validation for determination of eptifibatide acetate in bulk drug substance and pharmaceutical dosage forms

A new, rapid, economical and isocratic reverse phase high performance liquid chromatography (RP-HPLC) method was developed for the determination of eptifibatide acetate, a small synthetic antiplatelet peptide, in bulk drug substance and pharmaceutical dosage forms. The developed method was validated as per of ICH guidelines. The chromatographic separation was achieved isocratically on C18 colum...

Analytical Method Development and Validation of Estimation Method for Sotalol Hydrochloride Tablets by Using Rp-hplc

The present investigation describes about a simple, economic, selective, accurate, precise Reverse phase High performance liquid chromatographic method for the estimation of Sotalol Hydrochloride in pharmaceutical dosage forms. Sotalol Hydrochloride was well eluted using a C18 column of dimension 100 × 4.6, 5μm and Mobile phase consisting of Acetonitrile: 20 mM Ammonium acetate buffer (pH-6): M...

RP-HPLC as an analytical method for the determination of bendamustine and its related impurities in bulk drug